Qualifications

• Ph.D. Biochemistry, Bioenergetics, Protein Purifications, Molecular Cell Biology & Metabolism.
  Postgraduate Study Director
  – Molecular Cell Biology & Gene Therapy.
  – Coordinator for Postgraduate Study Program “Developmental Biology & Cellular Signaling”.
• Associate Professor & Senior Research Scientist (Cellular Proteomics & Metabolic Disorders).
• Full Professor: Cellular Biochemistry, Molecular Medicine and Food Chemistry.

Career or Professional Bodies/Awards

• Associate Professor and Senior Research Scientist at Karolinska Institutet, Dept. of Laboratory Medicine, Stockholm (Sweden)
• Postdoctoral Research at Oslo University, Dept. of Biology, Oslo (Norway)
• Postdoctoral Research at Royal Danish Veterinary and Agriculture University (KVL), Dept. of Plant Physiology, Copenhagen (Denmark)
• Assistant Professor at Stockholm University, Arrhenius Laboratories, Biochemistry Dept., Stockholm (Sweden)
• Research Visitor at University of Birmingham, School of Biosciences (UK).
• Research Visitor at Turku University, Department of Applied Biosciences (Finland).
• Research Visitor at Uppsala University, Department of Molecular Cell Biology and Tumor Biology (Sweden).
• Research Visitor at University of Chile, Faculty of Medicine, Dept. of Molecular & Clinical Pharmacology (Chile).
• Research Visitor at University of Mainz, Department of Molecular Physiology (Germany).
• Research Visitor at COMSATS Institute of Information Technology (Pakistan).
• Research Visitor at United Arab Emirates University (UAEU), Pharmacology Department (Al Ain, UAE).
• Research Visitor at Harvard Medical School, Department of System Biology (USA).
• Research Visitor at Toronto University, Lunenfeld Research Institute (LTRI), (CANADA)

Current Teaching Module

• SF1510 – Basic Biology for Food Science and Technology (1^st Semester FST)
• SF2201 – Molecules to Materials

Current Research and/or Postgraduate Projects

• Screening for Natural Bioactive compounds from Brunei/Borneo Biodiversity Resources, applicable for Biotechnology Innovations.
• Biochemical and Cell Molecular Biology Characterization of Bioactive Compounds for Drug Discovery.

Research Interest

• Food and Nutritional Biosciences, Cellular and Medical Biotechnology, Human/Plant Biochemistry, Molecular Cell Biology, Molecular basis of Human Diseases and Cancer, Molecular Diagnostics, Tissue Communications and Cellular Signalling, Proteomics, Bioinformatics, and Genetics.

Other Achievements/ Most Prominent Publications

(Papers published last five years)

1. Mohammad, D.K., Nore, B.F., and Smith, C.I.E. (2017) Terminating B cell receptor signaling. Oncotarget 8(66): 109857-109858.
   
   
2. Gustafsson, M.O., Mohammad, D.K., Ylösmäki, E., Choi, H., Shrestha, S., Wang, Q., Nore, B.F., Saksela, K. and Smith, C.I.E. (2017) ANKRD54 preferentially selects Bruton’s Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) Domain Library.
   
   
3. Mohammad, D.K., Ali, R.H., Turunen, J.J., Nore, B.F., and Smith, C.I.E. (2016) B Cell Receptor (BCR) Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing. PLoS One 11(8): e0160255.
   
   
4. Mohammad, D.K., Nore, B.F., Gustafsson, M.O., Mohamed, A.J., and Smith, C.I.E. (2016) Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7. Int. J. Biochem. Cell Biol. 78: 63-74.
   
   
5. Ali, D., Mohammad, D.K., Mujahed, H. Jonson-Videsäter, K., Nore, B., Paul, C., and Lehmann, S. (2016) Anti-leukaemic effects induced by APR-246 are dependent on induction of oxidative stress and the NFE2L2/HMOX1 axis that can be targeted by PI#K and mTOR inhibitors in acute myeloid leukemia  cells. Br. J. Haematol. 174: 117-126.
   
   
6. Khoshnaw, N., Francis, B., Safar, B.M., Mahmood, S.S. and Nore, B.F. (2014) Cytogenetic Response in Chronic Myeloid Leukaemia Patients Treated with Imatinib Mesylate Homolog-Drugs: A 6 year’s Transitional Study. Journal of Cancer Therapy 5: 453-459.
   
   
7. Qaradaghy, S.H., Hawramy, T.A., Nore, B.F., Abdullah, K.H., Muhammad, R.A., Zangana, M.O., Saleh, J.M. and Ismael, D.N. (2014) Plication (LP) – A novel surgical strategy in complete rectal prolapse. BMC Surg 14: 17-22.
   
   
8. Hamada-Kawaguchi, N., Nore, B.F., Kuwada, Y., Smith, C.I. and Yamamoto, D. (2014) Btk29A promotes Wnt4 signalling in the niche to terminate germ cell proliferation in Drosophila. Science 343 (6168): 294-297.
   
   
9. Huenchuguala, S., Muñoz, P., Zavala, P., Villa, M., Cuevas, C., Ahumada, U., Graumann, R., Nore, B.F., Couve, E., Mannervik, B., Paris, I. and Segura-Aguilar, J. (2014) Glutathione transferase mu 2 protects glioblastoma cells against aminochrome toxicity by preventing autophagy and lysosome dysfunction. Autophagy 10: 1-10.
   
   
10. Mohammad, D.K., Nore, B.F., Hussain, A., Gustafsson, M.O., Mohamed, A.J. and Smith, C.I. (2013) Dual phosphorylation of Btk by Akt/PKB Provides Docking for 14-3-3ζ, Regulates Shuttling and Attenuates both Tonic and Induced Signaling in B Cells. Mol Cell Biol  33: 3214-3226.
    
    
11. Vargas, L., Hamasy, A., Nore, B.F. and Smith, C.I.E. (2013) Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity, and inflammatory diseases. Scand J Immunol 78: 130-139.
    
    
12. Rashid, B.M., Rashid, N.G., Schulz, A., Lahr, G. and Nore, B.F. (2013) A novel missense mutation in the CLCN7 gene linked to benign autosomal dominant osteopetrosis: a case series. J Med Case Rep 7: 7-14.
    
    
13. Hussain, A., Mohammad, D.K., Gustafsson, M.O., Uslu, M., Hamasy, A., Nore, B.F., Mohamed, A.J. and Smith, C.I. (2013) Signaling of the ITK (IL2-inducible T-cell kinase)-SYK fusion kinase is dependent on adapter SLP-76 (SH2 domain-containing leukocyte protein of 76 kD) and on the adapter function of the kinases SYK/ZAP70 (zeta-chain [TCR] associated protein kinase 70 kD). J Biol Chem 288: 7338-7350.

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